CLR4SUV39H1 UBIQUITINATION AND NON-CODING RNA MEDIATE TRANSCRIPTIONAL SILENCING OF HETEROCHROMATIN VIA SWI6 PHASE SEPARATION

Clr4SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing of heterochromatin via Swi6 phase separation

Abstract Transcriptional silencing by RNAi paradoxically relies on transcription, but how the transition from transcription to silencing is achieved has remained unclear.The Cryptic Loci Regulator complex (CLRC) in Schizosaccharomyces pombe is a cullin-ring E3 ligase required for silencing that is recruited by RNAi.We found that the merrick backcou

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Modulator structures for radio-on-fiber applications

Traditional electro-optic modulators are not optimized for bandpass applications such flexcon reverse osmosis water storage tank as radio-on-fiber delivery systems due to their limited electro-optic response.This paper presents a resonant electrode structure that can be employed in optical modulator designs to enhance the electro-optic response of

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